Precision check of how kids push to poop (defecation) in dyssynergic defecation
Official title: Precision Evaluation of Defecation Dynamics in Children with Dyssynergic Defecation
Funded at Children's Hosp of Philadelphia · NIH-11448050 · Data updated 2026-11-12
A child-friendly study uses a tiny, electronic stool-shaped device to watch how kids with certain bowel problems push and coordinate during bowel movements.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 14, 2026 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $400,839 |
| NIH project number | 1R01DK144569-01A1 |
| Project ID | NIH-11448050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and young people with dyssynergic defecation, including ages from early childhood through adolescence.
✕Less likely to help
Children without functional constipation or without dyssynergic defecation are unlikely to benefit from this study.
What this research studies
This study focuses on children with dyssynergic defecation to understand the mechanics of defecation using a novel Fecobionics device that records pressures, shape, and movement inside the rectum and anal canal. The researchers aim to identify distinct subtypes of dyssynergia by analyzing how the pelvic floor and anal muscles coordinate during evacuation. The approach will compare real-time device measurements with traditional tests to find clearer links between symptoms and underlying mechanisms. The goal is to improve diagnostic accuracy and tailor treatments so that kids experience relief and fewer psychological and bowel-related problems.
Why it matters
Potential benefit: If successful, this could lead to better, more personalized diagnostics and treatments for children with constipation due to dyssynergic defecation.
How similar studies have gone: Prior adult studies suggest the device can reveal subtypes not detected by standard tests, but pediatric validation is still emerging.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Mousa, Hayat — Children's Hosp of Philadelphia
- Study coordinator: Mousa, Hayat
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.