Precise measure of how CP affects movement to guide treatment
Official title: Precise characterization of selective motor control in cerebral palsy
Funded at Children's Hosp of Philadelphia · NIH-11465476 · Data updated 2026-11-12
Aims to create precise, child-friendly ways to measure selective motor control in cerebral palsy so treatment can be tailored to each child.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $482,901 |
| NIH project number | 1R01HD121028-01A1 |
| Project ID | NIH-11465476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children with cerebral palsy, especially those with variability in motor control, who are within the 0-21 age range.
✕Less likely to help
Children whose CP motor patterns do not fit the study's measurement approach or who are outside the age range may not benefit.
What this research studies
This project focuses on children with cerebral palsy and seeks to describe how their muscles activate during movement, using new methods to capture specific patterns like co-activation and overflow. By turning complex motor signals into clear, personalized profiles, the team hopes to predict which treatments will help each child the most. The study will involve detailed motor assessments in young children to map impairment patterns and test how these measurements relate to treatment outcomes. If successful, clinicians could use these personalized measures to choose therapies that fit a child’s unique motor profile.
Why it matters
Potential benefit: If successful, the work could lead to more effective, individualized treatment plans for children with CP.
How similar studies have gone: Previous work shows that precise motor profiling can inform treatment choices, but this project aims to advance measurement precision and predictive value.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Prosser, Laura Anne — Children's Hosp of Philadelphia
- Study coordinator: Prosser, Laura Anne
Related research
Other NIH-funded projects on the same topics.
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Measuring how kids with cerebral palsy adapt their walking
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Non-invasive spinal stimulation to help kids with cerebral palsy move and reduce stiffness
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This research looks at how hindfoot problems in adults with cerebral palsy behave over time after childhood surgeries and what factors influence their lasting function.
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Dynamic Brain Imaging of Cerebral Palsy Gait
This project uses advanced brain and spinal imaging to understand how cerebral palsy affects the way young people plan and control their leg movements during walking.
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Understanding how spinal development is affected in cerebral palsy and finding ways to ease spasticity
Researchers are studying why spastic cerebral palsy causes tight muscles and reflexes and are testing a noninvasive treatment to help reduce these symptoms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.