NIH-funded research R21 grant

Post-diagnosis Changes in Body Weight and Body Composition in Kidney Cancer

Official title: Post-diagnosis changes in body composition and renal cell cancer survival

Funded at University of California Berkeley · NIH-11373745 · Data updated 2026-11-12

A research study follows people with clear cell kidney cancer to see how their weight and body fat/muscle change after diagnosis and how that relates to their survival.

More Body Composition research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley
NIH-funded
Lab location1 site (Berkeley, United States)
Project startJune 10, 2026
Project endMay 31, 2028
Funding year2026
Award (this year)$411,705
NIH project number1R21CA304922-01A1
Project IDNIH-11373745 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with clear cell renal cell carcinoma who have multiple weight and body composition assessments from diagnosis onward.

Less likely to help

Patients without regular imaging or weight tracking may not directly benefit from the study insights.

What this research studies

If you have clear cell renal cell carcinoma, this study will track your weight and body composition over time using scans and measurements after diagnosis. The researchers will look at how changes in fat and muscle, not just weight, relate to how long people live and how aggressive the cancer behaves. They will also examine tumor features to understand why these body changes occur, using a rigorous statistical approach to connect weight trajectories with outcomes. The goal is to clarify how weight and body makeup after diagnosis influence prognosis so clinicians can give better guidance. This is a large, observational study designed to generate insights for future care strategies.

Why it matters

Potential benefit: If successful, findings could help doctors tailor weight and body-composition guidance for ccRCC patients to support survival and quality of life.

How similar studies have gone: Preliminary work suggests weight and body composition relate to cancer outcomes, but this study is among the first to track post-diagnosis trajectories with molecular tumor features.

Where this research is happening

  • University of California Berkeley
    Berkeley, United States
    Active

Researchers

  • Principal investigator: Bradshaw, Patrick T — University of California Berkeley
  • Study coordinator: Bradshaw, Patrick T

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.