Population and evolution of recombining genes in bacteria
Official title: Population and evolutionary dynamics of recombining genes and alleles in bacteria
Funded at State University of New York at Albany · NIH-11329857 · Data updated 2026-11-12
This grant studies how bacteria swap genetic material to gain new traits, which can affect disease and antibiotic resistance, with results that could inform better treatments and tracking of bacterial threats.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Albany NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | August 9, 2021 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $415,788 |
| NIH project number | 2R35GM142924-06 |
| Project ID | NIH-11329857 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who have bacterial infections or are at risk for antimicrobial-resistant infections could indirectly benefit from better surveillance, treatment strategies, and public health interventions informed by this research.
✕Less likely to help
Healthy individuals without exposure to bacterial infections are unlikely to benefit directly from this basic science study.
What this research studies
This project explores how bacteria shuffle DNA to create new genotypes and traits, using population genomics, phylogenetics, experimental evolution, and computational modeling. By examining different recombination systems across bacteria, researchers aim to understand how these processes drive antibiotic resistance and adaptation to new environments. The work combines data analysis, simulations, and experiments to reveal the mechanisms and consequences of recombination for bacterial evolution. Insights from this research could help predict outbreak dynamics and guide the development of strategies to counter antimicrobial resistance.
Why it matters
Potential benefit: Gains in understanding bacterial evolution could improve how we prevent and treat infections and manage antimicrobial resistance.
How similar studies have gone: Previous work in microbial genomics and experimental evolution has yielded insights into recombination and resistance, suggesting this approach can be fruitful.
Where this research is happening
-
State University of New York at Albany
Albany, United States Active
Researchers
- Principal investigator: Andam, Cheryl Marie P — State University of New York at Albany
- Study coordinator: Andam, Cheryl Marie P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.