PIDTC: a shared network to improve care for inherited immune disorders
Primary Immune Deficiency Treatment Consortium (PIDTC): A resource to drive scientific and clinical advances related to the treatment of inborn errors of immunity
Creating a shared database and tools to help doctors and researchers improve care for people with inherited immune disorders like SCID, CGD, and Wiskott–Aldrich across the US and Canada.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11181593 on NIH RePORTER |
What this research studies
As a patient with an inherited immune disorder, this project brings together medical records and clinical experience from 49 hospitals so doctors can learn which treatments work best over time. The team is organizing the PIDTC database, adding tools to make it easier for clinicians and researchers to access and use data, and expanding the resource to answer more questions about treatments and long-term outcomes. The effort covers children and adults with conditions such as SCID, CGD, Wiskott–Aldrich syndrome, and primary immune regulatory disorders and includes bone marrow transplant and gene/cell therapy experiences. The goal is to sustain and grow the network so more patients and centers can contribute and benefit.
Who could benefit from this research
Good fit: People of any age diagnosed with inborn errors of immunity (for example SCID, CGD, Wiskott–Aldrich syndrome, or primary immune regulatory disorders) who are treated at or can share records with participating centers.
Not a fit: People without an inherited immune disorder or whose care and records are not shared with the PIDTC network are unlikely to receive direct benefit from this resource.
Why it matters
Potential benefit: Could lead to faster, more informed treatment choices, better long-term outcomes, and clearer guidance for people with inherited immune disorders.
How similar studies have performed: The PIDTC has operated since 2009 and its aggregated data have already informed treatment decisions and outcomes, so this is an expansion of an established effort rather than an untested approach.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Dvorak, Christopher Craig — University of California, San Francisco
- Study coordinator: Dvorak, Christopher Craig
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.