Personalized computer training to reduce anxious thinking in kids and teens

Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety

NIH-funded research University of Denver (Colorado Seminary) · NIH-10495445

This project offers a personalized computer program to help children and teens with anxiety learn to interpret uncertain situations in calmer, less threatening ways.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Denver (Colorado Seminary) NIH-funded
Lab location1 site (Denver, United States)
Project IDNIH-10495445 on NIH RePORTER

What this research studies

If your child has anxiety, they would use computer exercises that present unclear situations and give corrective feedback when they choose a threatening interpretation so they learn to pick more neutral interpretations. The program is tailored to each young person and delivered over multiple sessions to change automatic thinking patterns. Researchers will measure whether changes in interpretation style lead to reductions in anxiety symptoms. The work focuses on clinically anxious children and adolescents and may include in-person or remote computerized sessions.

Who could benefit from this research

Good fit: Clinically anxious children and adolescents who can complete computer-based tasks and whose caregivers consent to participation are the ideal candidates.

Not a fit: Children with severe comorbid psychiatric conditions, those unable to use computerized tasks, or youth whose anxiety is not driven by interpretation bias may not receive benefit.

Why it matters

Potential benefit: If successful, this could reduce anxious thinking and lower anxiety symptoms in children and teens using a brief, scalable, computer-based training.

How similar studies have performed: Related computerized cognitive bias modification has shown preliminary benefits in adults, but evidence in clinically anxious youth is limited.

Where this research is happening

Denver, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.