Personalized Care for Sepsis and Critical Illness
Precision Medicine in Sepsis with Critical Illness
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11126587
This work aims to find different types of sepsis in patients to help doctors choose the best treatments for each person.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11126587 on ClinicalTrials.gov |
What this research studies
Sepsis is a serious condition where the body's response to infection harms its own tissues and organs, often leading to death. Current treatments for sepsis haven't worked well for everyone because sepsis affects people differently. This project looks for specific patterns in patients' bodies, called 'phenotypes,' that show how their immune system is reacting. By understanding these patterns, doctors hope to match patients with the right treatments, moving towards more personalized care for sepsis and related critical illnesses like ARDS.
Who could benefit from this research
Good fit: Ideal candidates for future clinical applications of this work would be patients experiencing sepsis or acute respiratory distress syndrome (ARDS) in critical care settings.
Not a fit: Patients who do not have sepsis or ARDS would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to classify sepsis patients and guide doctors in selecting more effective, tailored treatments, potentially improving survival rates.
How similar studies have performed: Previous analyses of ARDS clinical trials have successfully identified distinct patient groups that respond differently to therapies, suggesting a similar approach could work for sepsis.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SINHA, PRATIK — WASHINGTON UNIVERSITY
- Study coordinator: SINHA, PRATIK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome