NIH-funded research NIH-funded research

Peer support and digital CBT to help adolescents and young adults with sickle cell pain

Official title: Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy

Funded at University of Pittsburgh at Pittsburgh · NIH-11618674 · Data updated 2026-11-12

A multisite study will test a digital cognitive behavioral therapy program for Black adolescents and young adults with sickle cell pain, guided by peer supporters.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startAugust 10, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$351,124
NIH project number3UH3HL165839-04S1
Project IDNIH-11618674 on NIH RePORTER

Who could benefit from this research

Could help

Black adolescents and young adults with sickle cell disease who experience pain crises and are engaged with or able to engage with community-based organizations.

Less likely to help

Participants not experiencing significant pain or those unable to participate in digital/peer-supported programs may see limited benefit.

What this research studies

This project focuses on AYAs aged 16-39 with sickle cell disease who experience painful crises. It will pair participants with peer supporters and deliver a scalable, digital CBT program to reduce pain and stress and improve mood. The study uses a randomized design to compare the digital CBT with personalized peer support against usual care, aiming to enhance engagement and adherence through community-based organizations. Outcomes will include pain, mood, and functioning, with data collected remotely across several sites. If successful, it could make effective, accessible pain management more available to this high-need group.

Why it matters

Potential benefit: If successful, this approach could reduce pain and improve mood and daily functioning for Black AYAs with SCD.

How similar studies have gone: Prior work shows digital CBT can reduce stress and pain in chronic conditions, and peer-supported digital therapies are feasible and acceptable in SCD; this study builds on that foundation.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Rollman, Bruce Lawrence — University of Pittsburgh at Pittsburgh
  • Study coordinator: Rollman, Bruce Lawrence

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.