Peer-led 'Game Changers' program to boost cervical cancer screening in Uganda

A Hybrid Implementation-Effectiveness Trial of Game Changers for Cervical Cancer Prevention in Uganda

NIH-funded research Rand Corporation · NIH-11404688

This project offers a peer-led seven-session program that helps women in Uganda encourage friends and family to get low-cost cervical cancer screening with VIA.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRand Corporation NIH-funded
Lab location1 site (Santa Monica, United States)
Project IDNIH-11404688 on NIH RePORTER

What this research studies

If you join, you would be part of a group led by women who have already been screened and trained to share accurate information, reduce stigma, and gently encourage screening within their social networks. The program uses seven peer-led group sessions that teach communication and dispel myths about cervical cancer and screening. The team will run a randomized trial in Ugandan communities to see whether women reached through these networks actually go for VIA screening and to learn how the program can be sustained. Researchers will also follow participants over time to track screening uptake and practical challenges to rolling the program out more widely.

Who could benefit from this research

Good fit: Ideal candidates are women in participating Ugandan communities who have recently had a cervical cancer screen and are willing to join peer groups, as well as unscreened women in their social networks who can be encouraged to attend VIA screening.

Not a fit: Women living outside the study areas, those already up-to-date with cervical screening, or those unable to take part in group sessions are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, this approach could raise screening rates, help detect precancer earlier, and reduce deaths from cervical cancer in Ugandan communities.

How similar studies have performed: A prior pilot randomized trial (R21) showed large increases in screening among network members, so this larger trial builds on promising early results.

Where this research is happening

Santa Monica, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerCancer AdvocacyCancer CauseCancer ControlCancer Control Science
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.