NIH-funded research R01 grant

Patient-tailored physical activity plan for older women with gynecologic cancer during chemotherapy

Official title: PATIENT-TAILORED PHYSICAL ACTIVITY INTERVENTION AMONG OLDER WOMEN WITH GYNECOLOGIC CANCERS UNDERGOING CHEMOTHERAPY (FIT4TREATMENT)

Funded at Northwestern University · NIH-11324527 · Data updated 2026-11-12

A remotely delivered, personalized 12-week physical activity program helps older women undergoing chemotherapy feel stronger and maintain daily function.

More Chemotherapy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startMay 1, 2023
Project endApril 30, 2028
Funding year2026
Award (this year)$716,390
NIH project number5R01AG081291-04
Project IDNIH-11324527 on NIH RePORTER

Who could benefit from this research

Could help

Older women with gynecologic cancer who are receiving adjuvant chemotherapy and can use mobile health tools.

Less likely to help

Patients without access to mobile devices or who cannot participate in remotely delivered programs may not benefit.

What this research studies

This project develops an mHealth-based physical activity program for older women with gynecologic cancer who are receiving chemotherapy. Using a multi-phase optimization strategy, participants will be randomly assigned to different combinations of program components to see which parts best boost physical activity and maintain it after the intervention. The study emphasizes accessibility, accommodating symptom-related fluctuations, and leveraging mobile technology to support activity at home. Results will inform which elements are most helpful to reduce frailty and improve quality of life during treatment.

Why it matters

Potential benefit: If successful, the program could help patients stay more active, feel better, and maintain independence during chemotherapy.

How similar studies have gone: Prior similar approaches show that tailored, remotely delivered activity programs can increase physical activity in older adults and cancer patients.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Barber, Emma — Northwestern University
  • Study coordinator: Barber, Emma

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.