Patient recruitment and sample collection for asthma and rheumatoid arthritis
Official title: Clinical Core
Funded at Benaroya Research Inst at Virginia Mason · NIH-11332434 · Data updated 2026-11-12
This project enrolls children with asthma and adults with rheumatoid arthritis to collect blood, nasal swabs, and sputum before and after respiratory viral infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Benaroya Research Inst at Virginia Mason NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | March 29, 2022 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $326,267 |
| NIH project number | 5U19AI167891-05 |
| Project ID | NIH-11332434 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children with asthma or allergic sensitization, healthy children without these conditions, adults with rheumatoid arthritis, and healthy adult controls who can attend local clinic visits and provide samples.
✕Less likely to help
People without asthma, allergic sensitization, or rheumatoid arthritis, or those unwilling to provide biological samples or attend follow-up visits, may not be eligible or likely to benefit directly.
What this research studies
If you join, the team will recruit and follow children with asthma, children with allergic sensitization, healthy children, adults with rheumatoid arthritis, and healthy adult volunteers over time. You'll be asked to provide blood, nasal swabs, and sputum at scheduled visits and again if you develop a respiratory viral infection. The Clinical Core handles processing, storing, and sharing samples with research teams while protecting your health information and complying with human-subjects rules. The work uses existing clinic networks, including the Childhood Asthma in Urban Settings network and the Benaroya Research Institute, to coordinate visits and sample handling.
Why it matters
Potential benefit: If successful, this work could help researchers understand how viral infections change immune responses in people with asthma and rheumatoid arthritis, which may guide better prevention and treatments.
How similar studies have gone: Other cohort and biospecimen-collection efforts have successfully linked infections to immune changes, though combining systems immunology across these specific vulnerable groups is relatively novel.
Where this research is happening
-
Benaroya Research Inst at Virginia Mason
Seattle, United States Active
Researchers
- Principal investigator: Buckner, Jane Hoyt — Benaroya Research Inst at Virginia Mason
- Study coordinator: Buckner, Jane Hoyt
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.