NIH-funded research R01 grant

Parenting-focused mindfulness to prevent adolescent substance use

Official title: Efficacy and Neurobiological Mechanisms of a Parenting-Focused Mindfullness Intervention to Prevent Adolescent Substance Use

Funded at George Mason University · NIH-11333716 · Data updated 2026-11-12

A parenting-focused mindfulness program for stressed parents of adolescents may lower family stress and help prevent substance use and related problems in teens.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorge Mason University
NIH-funded
Lab location1 site (Fairfax, United States)
Project startJuly 15, 2021
Project endMay 31, 2027
Funding year2026
Award (this year)$440,955
NIH project number5R01DA052427-05
Project IDNIH-11333716 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are parents of adolescents experiencing high stress who are willing to participate in a mindfulness-based program and associated assessments.

Less likely to help

Families not interested in mindfulness or those unable to participate in long-term follow-up may not benefit.

What this research studies

This project builds on prior pilot work showing that mindfulness for parents can reduce stress and improve parenting behaviors. It aims to run a larger trial to see if the benefits on parent stress and adolescent outcomes hold over time and across diverse families. The study will examine brain-related mechanisms, like how stress and parenting interact with neural pathways involved in emotion and decision-making. If successful, it could point to a developmentally tailored approach that families can use to reduce youth risk for substance use.

Why it matters

Potential benefit: If successful, families may experience less stress and better parenting, which could lower teens’ risk of starting or escalating substance use.

How similar studies have gone: Previous findings from a pilot trial showed positive effects on parent stress and some adolescent outcomes, suggesting potential for broader impact.

Where this research is happening

  • George Mason University
    Fairfax, United States
    Active

Researchers

  • Principal investigator: Chaplin, Tara M — George Mason University
  • Study coordinator: Chaplin, Tara M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.