Oral nicotine pouch use and its health effects across ages
Official title: Oral Nicotine Pouch Use and Potential Health Effects among AYAs
Funded at University of Nebraska Medical Center · NIH-11458541 · Data updated 2026-11-12
This project looks at how oral nicotine pouches are used by teens and young adults and what health effects they may have.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | July 1, 2026 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $422,125 |
| NIH project number | 1R21DA066670-01 |
| Project ID | NIH-11458541 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adolescents and young adults who have used or may use oral nicotine pouches, including ages roughly 12–25.
✕Less likely to help
Individuals who do not use or are unlikely to use ONPs may not directly benefit from the findings.
What this research studies
This study focuses on adolescents and young adults who use oral nicotine pouches, a discreet nicotine product. Researchers will combine large national survey data with biomarker information to understand patterns of use, risk factors, and potential health implications over time. The goal is to paint a clearer picture of how ONP exposure relates to health as AYAs transition into adulthood, using existing PATH data waves and biomarker samples. Findings could influence prevention messages and inform regulators about youth risk and protective factors.
Why it matters
Potential benefit: If successful, the research could improve understanding of ONP risks for youths and help guide policies and prevention efforts to protect adolescent health.
How similar studies have gone: Previous work with PATH data has yielded insights into youth tobacco product use, and similar approaches are likely to provide meaningful, comparable findings for ONPs.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Dai, Hongying Daisy — University of Nebraska Medical Center
- Study coordinator: Dai, Hongying Daisy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.