NIH-funded research R01 grant

Optimizing a Digital Program to Cut Sugary Drink and Added-Sugar Intake in Rural Appalachia

Official title: Optimizing iSIPsmarter: A Factorial Trial to Enhance Engagement and Effectiveness on Sugary Beverages and Weight among rural Appalachian adults

Funded at University of Virginia · NIH-11448002 · Data updated 2026-11-12

A fully digital, self-guided program helps adults in rural Appalachia reduce sugary drinks and foods high in added sugar to support healthier weight.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startApril 22, 2020
Project endApril 30, 2031
Funding year2026
Award (this year)$818,012
NIH project number2R01MD015033-06
Project IDNIH-11448002 on NIH RePORTER

Who could benefit from this research

Could help

Adults 21 years and older in rural Appalachian regions who are willing to use a digital, self-guided program and engage with text messages and online tools.

Less likely to help

Individuals who prefer in-person support, have no access to mobile/texting, or are unable to engage with digital tools may not benefit.

What this research studies

This project tests how to make iSIPsmarter more engaging and effective for adults 21+ in rural areas. It uses a factorial design to test different two-way text messaging and engagement strategies within a self-guided program that includes modules, daily SMS tracking, and weight monitoring. The aim is to keep people participating over the long term and improve their intake of sugar-sweetened beverages and added sugars without needing heavy staff support.

Why it matters

Potential benefit: If successful, the program could lead to sustained reductions in sugary beverage and added-sugar intake, potentially improving weight and chronic disease risk in underserved rural communities.

How similar studies have gone: Prior work showed short-term improvements; this study builds on that by optimizing engagement for long-term success.

Where this research is happening

  • University of Virginia
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Zoellner, Jamie — University of Virginia
  • Study coordinator: Zoellner, Jamie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.