NIH-funded research R01 grant

Online guided self-help family-based treatment for adolescent anorexia nervosa

Official title: Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa

Funded at Stanford University · NIH-11587034 · Data updated 2026-11-12

A study is testing a guided self-help version of a proven family-based therapy to help adolescents with anorexia nervosa receive effective treatment more efficiently in real-world clinics.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 20, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$127,237
NIH project number3R01MH130388-05S1
Project IDNIH-11587034 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents with anorexia nervosa and their families who have access to participating clinics and are candidates for family-based treatment.

Less likely to help

Patients who do not engage with family-based treatment or guided self-help formats may not benefit.

What this research studies

This project tests whether guided self-help for family-based treatment can deliver similar improvements in eating-related thoughts and weight for adolescents with anorexia nervosa, but more efficiently than traditional therapy. It builds on a prior multisite study showing comparable outcomes with greater efficiency, and it plans to confirm these results in general clinical settings. The study also looks at therapist attitudes toward the guided self-help approach to understand how it could be scaled. Conducted at multiple sites with rigorous implementation science aims, the trial emphasizes real-world applicability and feasibility. Participants are adolescents with anorexia nervosa and their families who would otherwise access standard care.

Why it matters

Potential benefit: If successful, more adolescents could receive effective treatment for anorexia nervosa more quickly and with fewer resources.

How similar studies have gone: Prior trials showed similar clinical improvements between guided self-help and standard therapy with good recruitment and safety profiles.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Lock, James D — Stanford University
  • Study coordinator: Lock, James D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.