NIH-funded research R01 grant

Online guided family-based program for adolescents with anorexia nervosa

Official title: Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa

Funded at Stanford University · NIH-11385617 · Data updated 2026-11-12

This project offers an online guided family-based program to help adolescents with anorexia nervosa improve symptoms while using much less therapist time than standard family therapy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 20, 2022
Project endJuly 31, 2027
Funding year2025
Award (this year)$131,269
NIH project number3R01MH130388-04S1
Project IDNIH-11385617 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents with anorexia nervosa who are medically stable for outpatient treatment, have an adult caregiver willing to participate, and can use online tools would be ideal candidates.

Less likely to help

Adults, patients requiring inpatient or medical stabilization, or those without caregiver support or reliable internet access may not benefit from this outpatient online approach.

What this research studies

You and your family would be offered a guided self-help version of Family-Based Treatment delivered online and compared to therapist-delivered family therapy in typical clinical settings. Families will be enrolled and followed over time while researchers track weight, eating-related thoughts and behaviors, safety, and how much therapist time each approach requires. The study builds on pilot work that showed similar clinical improvements but with the guided program using about 75% less therapist time. The goal is to confirm these findings in a larger, generalizable sample so more families could access effective care.

Why it matters

Potential benefit: If successful, this program could expand access to effective family-based care for teen anorexia and reduce the amount of clinician time needed.

How similar studies have gone: Earlier case series, pilot studies, and a multisite randomized feasibility trial found similar clinical improvements for the guided program compared with standard family therapy and much greater efficiency in therapist time.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Lock, James D — Stanford University
  • Study coordinator: Lock, James D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.