Omega PF device: a new, easier surgical option for drug-resistant GERD
Official title: Readying the commercialization of Omega device as an improved safe and efficacious treatment for drug-failed GERD patients
Funded at Aplos Medical INC · NIH-11403848 · Data updated 2026-11-12
A new medical device aims to replace complicated GERD surgery with a simpler, safer procedure for people whose reflux isn’t controlled by medicines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aplos Medical INC NIH-funded |
| Lab location | 1 site (Eden Prairie, United States) |
| Project start | September 2, 2025 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $429,295 |
| NIH project number | 5SB1DK143853-02 |
| Project ID | NIH-11403848 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with GERD who do not respond to medications and are considering surgery.
✕Less likely to help
Patients whose GERD is not related to the LES valve dysfunction or who cannot undergo surgery may not benefit.
What this research studies
This project focuses on bringing the Omega PF one-way valve device to market as a surgical option for patients with GERD who do not respond to drugs. It builds on early clinical findings that the device is simple to implant, effective at controlling reflux, and has a favorable safety profile. The team plans commercialization activities, including refining the procedure and ensuring it can be adopted broadly by foregut surgeons in standard clinical settings. If successful, this could offer a less morbid alternative to traditional fundoplication for many patients.
Why it matters
Potential benefit: If successful, patients with drug-failed GERD could have a safer, easier surgical option that reduces reflux and improves quality of life.
How similar studies have gone: Early clinical results show the device to be simple, effective, and safe, with the potential to be widely adopted.
Where this research is happening
-
Aplos Medical INC
Eden Prairie, United States Active
Researchers
- Principal investigator: Tihon, Claude Nmn — Aplos Medical INC
- Study coordinator: Tihon, Claude Nmn
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.