Noninvasive monitoring to prevent heart failure hospitalizations in adults
Official title: Acute Decompensation Avoidance in Heart Failure Patients
Funded at Barron Associates, INC. · NIH-11309272 · Data updated 2026-11-12
A new approach uses noninvasive methods to track heart failure changes at home and in hospital to prevent urgent worsening and readmissions.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Barron Associates, INC. NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | August 15, 2026 |
| Project end | August 14, 2027 |
| Funding year | 2026 |
| Award (this year) | $351,388 |
| NIH project number | 1R43HL184377-01 |
| Project ID | NIH-11309272 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults 21 years and older with acute decompensated heart failure who are hospitalized or under home monitoring.
✕Less likely to help
Patients without heart failure or those not eligible for noninvasive hemodynamic monitoring may not benefit.
What this research studies
This project focuses on improving how we monitor adults with acute decompensated heart failure by tracking hemodynamic changes without invasive procedures. It aims to translate home-based signals and noninvasive data into early interventions that could keep patients out of the hospital. The study will explore devices or methods that provide timely information beyond symptoms, guiding clinicians on when to adjust treatment. If successful, patients could experience fewer hospital stays and better overall management of their condition.
Why it matters
Potential benefit: If successful, patients with acute heart failure may have fewer hospitalizations and better early detection of deterioration.
How similar studies have gone: Prior noninvasive monitoring approaches like remote hemodynamic monitoring have shown potential to reduce admissions, but broader, cost-effective strategies are still being investigated.
Where this research is happening
-
Barron Associates, INC.
Charlottesville, United States Active
Researchers
- Principal investigator: Clark, Brian R — Barron Associates, INC.
- Study coordinator: Clark, Brian R
Related research
Other NIH-funded projects on the same topics.
-
AI-supported heart failure diagnosis and management in Rwanda
Aiming to help people with suspected heart failure in Rwanda get faster, more accurate diagnoses and better care using AI-guided ultrasound and care protocols.
-
AI-assisted heart failure diagnosis in Rwanda using focused ultrasound
An NIH-funded project will test whether AI-enhanced, easy-to-use heart ultrasound can help non-experts diagnose and manage heart failure in Rwanda.
-
HF endotypes in heart failure using ethical multi-modal AI and molecular data
A patient-friendly project that uses advanced AI and multiple kinds of health data to identify distinct heart failure subtypes that could guide personalized care.
-
Triple gene therapy approach to heal the heart after a heart attack
A new therapy combines three genetic approaches delivered by a virus to help the heart heal after a heart attack.
-
Digital-first heart failure care delivery in Uganda
A targeted program in Uganda tests a digital care plan to help people with heart failure manage their symptoms at home.
-
Digital-first heart failure care delivery in Uganda
A study to test digital self-care tools to help people with heart failure in Uganda manage symptoms and stay healthier.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.