NIH Open Measures Network: better brain health measures for Alzheimer's prevention trials
Official title: THE NIH Open Measures Network Initiative (OMNI): Evaluating and Advancing Cognitive Measures for AD/ADRD Prevention Trials
Funded at Pennsylvania State University, the · NIH-11382815 · Data updated 2026-11-12
A national initiative to create open, flexible tools that measure cognitive change in people at risk for Alzheimer's and related dementias to improve prevention research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | August 1, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $7,933,569 |
| NIH project number | 5U24AG092760-02 |
| Project ID | NIH-11382815 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers and clinicians studying midlife individuals at risk for AD/ADRD who need better cognitive measurement tools.
✕Less likely to help
There may be no direct benefit to individual patients participating unless they are part of a related prevention study using the measures developed.
What this research studies
This project builds a network to develop and validate brain health measures that accurately track cognitive changes before dementia symptoms appear. It creates four scientific cores (Data, Measures, Applied Validity, Dissemination) plus an Administrative Core to coordinate work and governance. A publicly available inventory of measurement tools will be published and updated regularly, with new tools developed as needed. The effort aims to make cognitive measures more reliable and widely usable across different study settings.
Why it matters
Potential benefit: If successful, researchers will have better, openly available measures to detect early brain changes and test prevention strategies.
How similar studies have gone: Similar efforts have started to compile and validate cognitive measures, with growing adoption of open-access tools in prevention research.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Sliwinski, Martin J — Pennsylvania State University, the
- Study coordinator: Sliwinski, Martin J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.