New treatment for lung injuries caused by sulfur mustard exposure

A Novel, Host-Directed Therapeutic for the Treatment of Sulfur Mustard Induced Lung Injury

NIH-funded research Cmtx Biotech, INC. · NIH-11008227

This study is testing a new oral medication called incyclinide to help people who have lung injuries from exposure to sulfur mustard, aiming to improve their breathing and overall recovery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCmtx Biotech, INC. NIH-funded
Lab location1 site (Kings Park, United States)
Project IDNIH-11008227 on NIH RePORTER

What this research studies

This research focuses on developing a novel therapeutic approach using a small-molecule drug called incyclinide to treat lung injuries caused by exposure to sulfur mustard, a harmful chemical agent. The treatment aims to modulate the body's response to the injury rather than just addressing the symptoms. Patients who have been exposed to sulfur mustard may experience severe respiratory issues, and this research seeks to provide a new option for managing those complications. The approach involves administering the drug orally, which could make it more accessible for patients in need.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced exposure to sulfur mustard and are suffering from related lung injuries.

Not a fit: Patients who have not been exposed to sulfur mustard or who have other unrelated respiratory conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from lung injuries due to sulfur mustard exposure.

How similar studies have performed: While the approach of using host-modulatory therapies is promising, this specific application for sulfur mustard-induced lung injury is novel and has not been extensively tested in prior research.

Where this research is happening

Kings Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Lung InjuryAcute Pulmonary InjuryAcute Respiratory Distress Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.