New tests for diagnosing invasive aspergillosis in immunocompromised patients
Official title: Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis
Funded at Duke University · NIH-11032935 · Data updated 2026-11-12
This study is working on a new, quick, and easy way to diagnose invasive aspergillosis, a serious infection that can affect people with weakened immune systems, by looking at how your body responds to the infection, so you can get the right treatment faster and feel better sooner.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | December 2, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $181,861 |
| NIH project number | 1K23AI187748-01 |
| Project ID | NIH-11032935 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are immunocompromised patients who are at risk for invasive aspergillosis.
✕Less likely to help
Patients who are not immunocompromised or those without a risk of invasive aspergillosis may not benefit from this research.
What this research studies
This research focuses on developing innovative, rapid, and noninvasive diagnostic tests for invasive aspergillosis (IA), a serious infection that often affects patients with weakened immune systems. By analyzing the body's genetic responses to the infection, the researchers aim to create accurate biomarkers that can help diagnose IA more effectively than current methods, which often require invasive procedures and can yield delayed results. The project will utilize existing samples and involve enrolling patients to monitor their responses to treatment, ultimately improving patient outcomes through timely antifungal therapy.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of invasive aspergillosis, significantly improving treatment outcomes and survival rates for affected patients.
How similar studies have gone: Previous research has shown promise in developing noninvasive diagnostic methods for fungal infections, indicating that this approach could be effective.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Steinbrink, Julie Marie — Duke University
- Study coordinator: Steinbrink, Julie Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.