New technology to study kidney cells at a single-cell level
Official title: Single-cell Cyclic Multiplex in Situ Tagging to Advance Kidney Research
Funded at State University New York Stony Brook · NIH-10790122 · Data updated 2026-11-12
This study is testing a new technology that helps scientists look closely at kidney cells from biopsy samples to better understand kidney diseases, which could lead to new insights and treatments for patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | September 22, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $337,284 |
| NIH project number | 1R21DK138409-01 |
| Project ID | NIH-10790122 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with kidney diseases who are undergoing biopsy procedures.
✕Less likely to help
Patients without kidney diseases or those not undergoing kidney biopsies may not benefit from this research.
What this research studies
This research focuses on developing a novel technology called single-cell spatial multiplex in situ tagging (MIST) to analyze kidney cells. By applying this technology to kidney biopsy samples, researchers aim to measure hundreds of proteins that are crucial for understanding kidney diseases. This approach will allow for a detailed examination of the unique cell types within the kidney, bridging the gap between gene expression and clinical diagnosis. Patients may benefit from insights gained about disease mechanisms and potential treatment targets.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for kidney diseases.
How similar studies have gone: Previous research has shown success with similar multiplexing technologies in other tissues, indicating potential for this novel approach in kidney research.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Wang, Jun — State University New York Stony Brook
- Study coordinator: Wang, Jun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.