New technology to study kidney cells at a single-cell level
Single-cell Cyclic Multiplex in Situ Tagging to Advance Kidney Research
This study is testing a new technology that helps scientists look closely at kidney cells from biopsy samples to better understand kidney diseases, which could lead to new insights and treatments for patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-10790122 on NIH RePORTER |
What this research studies
This research focuses on developing a novel technology called single-cell spatial multiplex in situ tagging (MIST) to analyze kidney cells. By applying this technology to kidney biopsy samples, researchers aim to measure hundreds of proteins that are crucial for understanding kidney diseases. This approach will allow for a detailed examination of the unique cell types within the kidney, bridging the gap between gene expression and clinical diagnosis. Patients may benefit from insights gained about disease mechanisms and potential treatment targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with kidney diseases who are undergoing biopsy procedures.
Not a fit: Patients without kidney diseases or those not undergoing kidney biopsies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for kidney diseases.
How similar studies have performed: Previous research has shown success with similar multiplexing technologies in other tissues, indicating potential for this novel approach in kidney research.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Wang, Jun — State University New York Stony Brook
- Study coordinator: Wang, Jun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.