New methods to identify and treat sepsis
Novel approaches to detect and treat sepsis
This study is working on new ways to quickly and accurately detect and treat sepsis, a serious infection, using advanced tools like tiny robots and special devices, so that even places with fewer resources can help patients get the care they need.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project ID | NIH-10908308 on NIH RePORTER |
What this research studies
This research focuses on improving the detection and treatment of sepsis, a life-threatening condition caused by bacterial infections. The team aims to develop innovative technologies, including hybrid bio-inorganic nanobots and CRISPR-based devices, to enhance the accuracy of sepsis diagnosis and treatment. By engineering specific bacteriophages and utilizing microfluidic technologies, the project seeks to create portable diagnostic tools that can be used even in resource-limited settings. The research will involve testing these new methods on blood samples to ensure their effectiveness in identifying pathogens responsible for sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research are hospitalized patients who are at risk of developing sepsis due to bacterial infections.
Not a fit: Patients with non-bacterial infections or those who are not hospitalized may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis and treatment of sepsis, potentially saving thousands of lives.
How similar studies have performed: Previous research has shown promise in using CRISPR and bacteriophage technologies for pathogen detection, indicating a potential for success in this novel approach.
Where this research is happening
Riverside, United States
- University of California Riverside — Riverside, United States (Active)
Researchers
- Principal investigator: Chen, Juhong — University of California Riverside
- Study coordinator: Chen, Juhong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.