NIH-funded research R01 grant

New imaging technology to understand tumors and other diseases

Official title: Preclinical Electron Paramagnetic Resonance Tumor Imager

Funded at University of Denver (Colorado Seminary) · NIH-10881902 · Data updated 2026-11-12

This study is testing a new, portable imaging system that can help doctors see important details about tumors and other health issues by measuring things like oxygen levels and free radicals, which could lead to better treatment options for patients with cancer and other conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Denver (Colorado Seminary)
NIH-funded
Lab location1 site (Denver, United States)
Project startJuly 8, 2021
Project endJune 30, 2026
Funding year2024
Award (this year)$505,011
NIH project number5R01CA262159-04
Project IDNIH-10881902 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients with cancer, acute lung injury, or other conditions related to oxidative stress and free radical activity.

Less likely to help

Patients with conditions unrelated to oxidative stress or those who do not have access to the imaging technology may not benefit from this research.

What this research studies

This research focuses on developing a novel electron paramagnetic resonance (EPR) imaging system that can measure important physiological parameters like oxygen levels and redox status in tumors and other conditions. By utilizing advanced techniques, the study aims to provide insights into how free radicals affect cancer and other diseases, potentially guiding treatment decisions. The system will be compact and transportable, making it suitable for both clinical and pharmaceutical applications. The research will involve testing this technology in mouse models to assess its effectiveness in various medical scenarios, including cancer treatment and acute lung injury.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for cancer and other serious conditions by providing real-time insights into tumor biology.

How similar studies have gone: Other research has shown promise in using EPR imaging techniques, suggesting that this approach could be a significant advancement in understanding and treating various diseases.

Where this research is happening

  • University of Denver (Colorado Seminary)
    Denver, United States
    Active

Researchers

  • Principal investigator: Eaton, Gareth R — University of Denver (Colorado Seminary)
  • Study coordinator: Eaton, Gareth R

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.