New imaging technology for analyzing tissue samples in patients
Official title: Development of a New Multiplexed Imaging Strategy for Immunoprofiling using Raman-Active Nanoparticles
Funded at University of Southern California · NIH-10980211 · Data updated 2026-11-12
This study is testing a new imaging technology that uses special tiny particles to give doctors detailed information about your tissue samples, helping them understand your unique disease better and create more personalized treatment plans just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $643,522 |
| NIH project number | 1R01CA293950-01 |
| Project ID | NIH-10980211 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with cancer or autoimmune diseases who require detailed molecular profiling for treatment decisions.
✕Less likely to help
Patients with conditions that do not involve tissue analysis or those who are not undergoing treatment requiring molecular profiling may not benefit from this research.
What this research studies
This research focuses on developing a novel imaging technology that utilizes Raman-active nanoparticles to provide detailed molecular information from tissue samples. By combining high-resolution imaging with advanced molecular profiling, this approach aims to enhance the understanding of a patient's unique disease characteristics. Clinicians will be able to use this technology on tissue sections already prepared for standard histology, allowing for better patient stratification and personalized treatment plans. The goal is to improve the prediction of disease aggressiveness and treatment responses based on the molecular profiles obtained from the patient's tissues.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with various diseases, particularly cancers and autoimmune conditions.
How similar studies have gone: Other research has shown promising results using similar imaging techniques for molecular profiling, indicating potential for success in this novel approach.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Zavaleta, Cristina L. — University of Southern California
- Study coordinator: Zavaleta, Cristina L.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.