New coating for hemodialysis catheters to prevent infections.
Official title: Ceragenin-based antimicrobial coating to tackle hemodialysis catheter-related infections.
Funded at N8 Medical, INC. · NIH-10602612 · Data updated 2026-11-12
This study is testing a new coating for hemodialysis catheters that helps prevent infections, making it safer and more effective for patients who need dialysis.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | N8 Medical, INC. NIH-funded |
| Lab location | 1 site (Dublin, UNITED STATES) |
| Project start | September 12, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $299,155 |
| NIH project number | 1R43DK133005-01A1 |
| Project ID | NIH-10602612 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing hemodialysis who are at risk for catheter-related infections.
✕Less likely to help
Patients who do not use hemodialysis catheters or have alternative treatment options for their kidney condition may not benefit from this research.
What this research studies
This research focuses on developing a novel antimicrobial coating for hemodialysis catheters using ceragenins, which are designed to mimic natural antimicrobial peptides. The goal is to reduce the risk of catheter-related infections, which are a significant concern for hemodialysis patients. The approach aims to enhance the effectiveness of existing treatments by preventing bacterial growth and sensitizing bacteria to antibiotics. By addressing the limitations of current antimicrobial strategies, this research seeks to improve patient outcomes and reduce healthcare costs associated with infections.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of infections related to hemodialysis catheters, improving patient safety and reducing hospitalization costs.
How similar studies have gone: While there have been various approaches to antimicrobial coatings, the use of ceragenins represents a novel strategy that has not been extensively tested in this specific application.
Where this research is happening
-
N8 Medical, INC.
Dublin, United States Active
Researchers
- Principal investigator: Brunner, Glenn — N8 Medical, INC.
- Study coordinator: Brunner, Glenn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.