New CAR-T Cell Therapy for Brain Cancer
Career Enhancement Program
This project is developing a new cell therapy to fight glioblastoma, a type of brain cancer, by targeting cancer cells and boosting the immune system.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11164766 on NIH RePORTER |
What this research studies
This project aims to test a new type of cell therapy called CAR-T for glioblastoma, a serious brain cancer. This special CAR-T cell therapy is designed to do two things: directly attack glioblastoma cells and also overcome the cancer's ability to suppress the immune system. Researchers will carefully check if this new treatment is safe, if it works, and how the body responds to it after it's given directly into the tumor or brain fluid. The hope is that this dual approach will lead to better results for patients with glioblastoma.
Who could benefit from this research
Good fit: Ideal candidates would be patients diagnosed with glioblastoma who might be eligible for novel cell therapies.
Not a fit: Patients without glioblastoma or those with other types of brain tumors would not directly benefit from this specific therapy.
Why it matters
Potential benefit: If successful, this new CAR-T cell therapy could offer an improved treatment option for glioblastoma, potentially leading to better patient outcomes.
How similar studies have performed: CAR-T cell therapies have shown success in treating other cancers, but this specific combination and approach for glioblastoma is novel and being tested for the first time.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Liau, Linda M — University of California Los Angeles
- Study coordinator: Liau, Linda M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.