Neurophotonic Advances to understand capillary dysfunction in stroke recovery
Official title: Neurophotonic Advances for Mechanistic Investigation of the Role of Capillary Dysfunction in Stroke Recovery
Funded at Boston University (Charles River Campus) · NIH-11392253 · Data updated 2026-11-12
A study using advanced brain-imaging and light-based techniques to understand how tiny blood vessels affect recovery after a stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 27, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $655,019 |
| NIH project number | 5R01NS127156-05 |
| Project ID | NIH-11392253 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who have experienced an ischemic stroke and are in the acute to chronic recovery phases.
✕Less likely to help
Patients without access to advanced imaging facilities or those outside the study’s monitoring windows may not benefit directly.
What this research studies
This project uses cutting-edge imaging methods to watch how brain blood vessels respond during stroke recovery, aiming to clarify why some patients regain function. It focuses on how capillaries and vascular changes influence brain signals measured by MRI and near-infrared light. By testing in the acute to chronic phases, it seeks to map neurovascular changes that accompany recovery. The findings could help tailor imaging-guided treatment to improve outcomes for stroke survivors.
Why it matters
Potential benefit: If successful, the work could improve how doctors monitor and guide stroke recovery using imaging, potentially leading to better-tailored therapies.
How similar studies have gone: Related imaging studies have shown promise in mapping neurovascular changes, but the specific link between capillary dysfunction and recovery remains to be clarified.
Where this research is happening
-
Boston University (Charles River Campus)
Boston, United States Active
Researchers
- Principal investigator: Boas, David a — Boston University (Charles River Campus)
- Study coordinator: Boas, David a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.