NIH-funded research R01 grant

Nationwide study on how air-borne radioactivity from particulate matter affects heart disease

Official title: A nationwide population-based study investigating the cardiovascular effects of exposure to particulate matter α-, β-, and γ-activities and individual radionuclides

Funded at Rutgers Biomedical and Health Sciences · NIH-11593237 · Data updated 2026-11-12

A nationwide study will look at how tiny radioactive particles in the air may influence heart disease and hospitalizations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startAugust 20, 2026
Project endJanuary 31, 2029
Funding year2026
Award (this year)$329,402
NIH project number7R01ES035390-04
Project IDNIH-11593237 on NIH RePORTER

Who could benefit from this research

Could help

Older adults and individuals with cardiovascular risk factors who live in areas with higher air-pollution exposure.

Less likely to help

Individuals with no exposure to ambient particulate matter or without cardiovascular risk factors may see limited direct benefit.

What this research studies

This project uses national health and air-monitoring data to understand whether radioactive components attached to particulate matter contribute to heart attacks, strokes, and related health issues. Researchers will analyze short- and long-term exposure to beta, alpha, and gamma radiation from ambient particles and see how these exposures relate to cardiovascular events and blood pressure. The study leverages large public datasets to explore whether radiation in air pollution worsens heart disease risk among Medicare enrollees and the general population. Insights could help identify more harmful air-pollution characteristics and possibilities for reducing cardiovascular harm.

Why it matters

Potential benefit: If successful, findings could inform air-quality standards and preventive strategies to protect heart health.

How similar studies have gone: Preliminary work has linked particulate matter to cardiovascular risk, but this study uniquely integrates radionuclide components and national-scale data.

Where this research is happening

  • Rutgers Biomedical and Health Sciences
    Newark, United States
    Active

Researchers

  • Principal investigator: Zanobetti, Antonella — Rutgers Biomedical and Health Sciences
  • Study coordinator: Zanobetti, Antonella

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.