Multifunctional ionic liquids to protect implants and promote healing
Official title: Multifunctional Ionic Liquid Application for Treatment of Peri-implant Diseases
Funded at University of Texas Dallas · NIH-11386632 · Data updated 2026-11-12
A study to test a special coating for dental implants that fights infection, reduces inflammation, and helps tissues heal around the implant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Dallas NIH-funded |
| Lab location | 1 site (Richardson, United States) |
| Project start | July 14, 2017 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $370,500 |
| NIH project number | 5R01DE026736-10 |
| Project ID | NIH-11386632 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with dental implants at risk for or experiencing peri-implant diseases may be eligible.
✕Less likely to help
Patients without dental implants or without peri-implant disease are unlikely to benefit.
What this research studies
This project explores a coating made from designer ionic liquids that can be applied to dental implants. It aims to kill bacteria on the implant surface, minimize damaging immune responses, and support tissue reattachment. The work builds on prior lab findings showing these coatings can remain stable on titanium and interact positively with the surrounding tissue. If successful, the coating could reduce complications like mucositis and peri-implantitis and improve long-term implant success.
Why it matters
Potential benefit: If successful, patients could experience fewer implant infections and better tissue healing around implants.
How similar studies have gone: Preliminary lab studies showed that the coatings can form stable implants and interact with tissue, but human studies are still needed.
Where this research is happening
-
University of Texas Dallas
Richardson, United States Active
Researchers
- Principal investigator: Rodrigues, Danieli — University of Texas Dallas
- Study coordinator: Rodrigues, Danieli
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.