Multi-Modal Wearable Sensor for Early Detection and Remote Monitoring of Cognitive Decline
Official title: A Multi-Modal Wearable Sensor for Early Detection of Cognitive Decline and Remote Monitoring of Cognitive-Motor Decline Over Time
Funded at Biosensics, LLC · NIH-11378570 · Data updated 2026-11-12
A wearable device and digital biomarkers aim to detect early cognitive changes and monitor cognitive-motor decline in adults with Alzheimer’s disease dementia.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | July 15, 2023 |
| Project end | March 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,245,571 |
| NIH project number | 5R44AG084487-03 |
| Project ID | NIH-11378570 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with Alzheimer’s disease dementia who can wear a multi-sensor device and participate in remote monitoring.
✕Less likely to help
Patients not able to wear or use a wearable device, or those without access to remote monitoring infrastructure, may see limited benefit.
What this research studies
This project develops PAMSys+ a wearable system that tracks daily activities and dual-task performance to identify subtle cognitive changes. It uses multiple sensors to capture physical and cognitive data remotely, enabling continuous monitoring outside clinical visits. The goal is to provide timely signals of decline to patients, families, and clinicians so care plans can adapt sooner. The approach focuses on populations affected by Alzheimer’s disease dementia and seeks to improve early diagnosis and ongoing tracking where access to traditional screening may be limited.
Why it matters
Potential benefit: If successful, patients could receive earlier detection of cognitive changes and more timely care adjustments through easy-to-use remote monitoring.
How similar studies have gone: Prior work shows wearable sensors can capture meaningful motor and cognitive signals, but robust early-detection tools remain an active area with mixed results.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.