MTX-001 for healing diabetic foot ulcers in people with diabetes
Official title: Evaluation of Efficacy and Safety of MTX-001 in Diabetic Foot Ulcers
Funded at Merakris Therapeutics INC · NIH-11315603 · Data updated 2026-11-12
A first–in–class biologic therapy called MTX-001 is being tested to help heal diabetic foot ulcers and reduce infection risk in adults with diabetes.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Merakris Therapeutics INC NIH-funded |
| Lab location | 1 site (Hillsborough, United States) |
| Project start | July 20, 2026 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,109,504 |
| NIH project number | 1R44DK146625-01 |
| Project ID | NIH-11315603 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with diabetes and a diabetic foot ulcer who meet the study criteria and are candidates for new therapies.
✕Less likely to help
Patients whose ulcers do not respond to MTX-001 or who experience intolerable side effects may not benefit.
What this research studies
If you have diabetes and a foot ulcer, this study is exploring MTX-001 as a new treatment option added to standard care. The trial will enroll adults with DFUs to receive MTX-001 and monitor healing, safety, and any adverse effects over time. Researchers will compare healing progress and safety signals to current care practices to see if MTX-001 offers an advantage. The goal is to improve wound healing, reduce infections, and potentially lower amputation risk for patients like you.
Why it matters
Potential benefit: If successful, MTX-001 could speed wound healing and lower complications for people with diabetic foot ulcers.
How similar studies have gone: Previous treatments for DFUs show limited healing in many patients, making new options like MTX-001 promising but still needing proof of benefit.
Where this research is happening
-
Merakris Therapeutics INC
Hillsborough, United States Active
Researchers
- Principal investigator: Ilagan, Roger — Merakris Therapeutics INC
- Study coordinator: Ilagan, Roger
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.