Mouse trait database for understanding human disease
Mouse Phenome Project
This project builds a public online database of detailed mouse traits to help researchers better understand and model human chronic diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-11321143 on NIH RePORTER |
What this research studies
From my perspective, this project collects well-documented measurements of mouse traits (like behavior, physiology, and disease signs) from many different mouse populations. Those measurements are gathered into a single public database with improved tools for searching, visualizing, and linking mouse findings to human genetics and disease-relevant measurements. The team works with many labs to integrate diverse datasets, standardize trait descriptions, and add user-friendly interfaces so non-experts can find relevant data. All data and tools are maintained at The Jackson Laboratory and shared openly to help researchers meet NIH data-sharing requirements and speed translation to human health.
Who could benefit from this research
Good fit: There is no patient enrollment; the work is most relevant to people with chronic illnesses or cognitive decline who want research that connects mouse findings to human health.
Not a fit: People seeking direct clinical treatment or immediate personal medical benefits would not be helped directly by this project.
Why it matters
Potential benefit: If successful, the resource could help researchers pick better mouse models and speed discovery of treatments for chronic and cognitive diseases.
How similar studies have performed: Existing mouse data resources, including prior Mouse Phenome efforts, have helped researchers compare models and find disease-linked traits, and this grant expands and modernizes that work.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Chesler, Elissa J — Jackson Laboratory
- Study coordinator: Chesler, Elissa J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.