NIH-funded research R01 grant

Monitoring symptoms to help women with breast cancer take their medications

Official title: Symptom Monitoring using Patient-Reported Outcomes to Optimize Medication Use (SyMPTOM)

Funded at Medical College of Wisconsin · NIH-10977779 · Data updated 2026-11-12

This study is for women with hormone receptor positive breast cancer who are taking hormone therapy, and it aims to help them stick to their medication by regularly checking in on their symptoms and offering support to make their treatment easier and more comfortable.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin
NIH-funded
Lab location1 site (Milwaukee, United States)
Project startAugust 6, 2024
Project endJuly 31, 2029
Funding year2024
Award (this year)$678,927
NIH project number1R01CA285925-01A1
Project IDNIH-10977779 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women diagnosed with hormone receptor positive breast cancer who are prescribed endocrine therapy and may be experiencing symptoms that hinder their medication adherence.

Less likely to help

Patients who are not undergoing endocrine therapy or those with early-stage breast cancer may not benefit from this research.

What this research studies

This research focuses on women diagnosed with hormone receptor positive breast cancer who are prescribed endocrine therapy. It aims to improve medication adherence by routinely collecting patient-reported symptom data and providing support from clinical pharmacy teams to manage these symptoms. By addressing barriers such as pain and menopausal symptoms, the study seeks to enhance the overall treatment experience and outcomes for patients. The approach combines routine symptom monitoring with proactive outreach to patients who may struggle with their medication regimen.

Why it matters

Potential benefit: If successful, this research could significantly improve medication adherence and overall survival rates for women with breast cancer.

How similar studies have gone: Previous research has shown that routine symptom monitoring and management can improve outcomes in similar patient populations, indicating a promising approach.

Where this research is happening

  • Medical College of Wisconsin
    Milwaukee, United States
    Active

Researchers

  • Principal investigator: Flynn, Kathryn E — Medical College of Wisconsin
  • Study coordinator: Flynn, Kathryn E

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.