Mobile cardiac rehabilitation for people with INOCA (ischemia without blocked arteries)
Official title: mHealth-CArdiac REhabilitation for INOCA (INOCA-CARE)
Funded at New York University School of Medicine · NIH-11128440 · Data updated 2026-11-12
This project offers a home-based mobile cardiac rehab program using a smartphone app and wearable trackers to help people with ischemia but no blocked coronary arteries (INOCA) reduce symptoms and improve daily function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $576,600 |
| NIH project number | 5R01HL170666-02 |
| Project ID | NIH-11128440 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults diagnosed with ischemia with no obstructive coronary arteries (INOCA) who have angina, shortness of breath, or fatigue and can use a smartphone and wearable device are the ideal candidates.
✕Less likely to help
People with unstable heart conditions, severe mobility limitations, those eligible for coronary revascularization, or those without access to a smartphone or internet may not be suitable and may not benefit.
What this research studies
If I join, I'll use a smartphone app and a wearable device for guided exercise, symptom tracking, and remote coaching instead of traveling to a clinic. The program mirrors key parts of traditional cardiac rehab—exercise counseling, activity monitoring, and health education—delivered at home. Researchers will track my symptoms, activity levels, and quality of life over time to see how I respond. The goal is to help people with INOCA overcome barriers like distance, cost, and caregiving demands so they can take part in rehab.
Why it matters
Potential benefit: If successful, this could reduce angina, breathlessness, and fatigue and improve daily functioning and quality of life for people with INOCA.
How similar studies have gone: Home- and mobile-based cardiac rehab has helped some patients with coronary disease, but mHealth programs have not been specifically tested in people with INOCA, so benefits in this group are still unproven.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Reynolds, Harmony R — New York University School of Medicine
- Study coordinator: Reynolds, Harmony R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.