Methods to improve epilepsy surgery by mapping brain networks
Scalable methods to quantify epileptic network and guide epilepsy surgery
This study is working on new ways to better understand how epilepsy affects the brain, which could help doctors plan surgeries for people with hard-to-control seizures, making treatments more effective and improving lives.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10949915 on NIH RePORTER |
What this research studies
This research aims to develop standardized methods to accurately map the brain networks involved in epilepsy, which can help guide surgical interventions for patients with uncontrolled seizures. By integrating non-invasive imaging techniques with invasive monitoring, the project seeks to create a comprehensive understanding of seizure origins and their spread. The goal is to establish a scalable infrastructure that allows these methods to be implemented widely in clinical practice, ultimately improving patient outcomes. The research will rigorously validate these methods to ensure they can effectively target and optimize epilepsy treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with epilepsy who have not responded to medical therapy and are considering surgical options.
Not a fit: Patients with well-controlled seizures or those who are not candidates for surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective epilepsy surgeries, reducing seizures and improving the quality of life for patients.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to improve surgical outcomes in epilepsy, indicating that this approach has potential for success.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Sinha, Nishant — University of Pennsylvania
- Study coordinator: Sinha, Nishant
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.