Measuring proteins in blood to improve personalized medicine for children with type 1 diabetes
Quantifying proteins in plasma do democratize personalized medicine for patients with type 1 diabetes
This study is working on better blood tests to help doctors find the right treatments for kids with type 1 diabetes by measuring important proteins, which could lead to improved care and management of the condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10891722 on NIH RePORTER |
What this research studies
This research focuses on developing advanced blood tests to measure proteins that can help personalize treatment for children with type 1 diabetes. By using a technique called liquid chromatography-tandem mass spectrometry, the researchers aim to create more accurate and sensitive assays for detecting important biomarkers. This could lead to better predictions and management of the disease, ultimately improving patient care. The study will also explore new methods to enhance the sensitivity of these tests, making them more effective for clinical use.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with type 1 diabetes.
Not a fit: Patients with type 1 diabetes who are older than 11 years may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for children with type 1 diabetes.
How similar studies have performed: Previous research using mass spectrometry for biomarker detection has shown promising results, indicating that this approach could be effective.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Hoofnagle, Andrew N — University of Washington
- Study coordinator: Hoofnagle, Andrew N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.