NIH-funded research R01 grant

Measuring blood vessel growth using advanced ultrasound techniques

Official title: Quantitative assessment of angiogenesis using ultrasound multiple scattering

Funded at North Carolina State University Raleigh · NIH-11088922 · Data updated 2026-11-12

This study is testing a new way to use ultrasound technology to better understand how new blood vessels form in conditions like cancer and heart disease, which could help doctors diagnose these issues more accurately.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorth Carolina State University Raleigh
NIH-funded
Lab location1 site (Raleigh, United States)
Project startJune 15, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$603,870
NIH project number5R01CA282648-03
Project IDNIH-11088922 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for cancers, particularly breast cancer, or those with atherosclerotic conditions.

Less likely to help

Patients with conditions that do not involve angiogenesis or those who are not at risk for the diseases being studied may not benefit from this research.

What this research studies

This research focuses on developing a new method to quantitatively assess angiogenesis, which is the formation of new blood vessels, using advanced ultrasound technology. By analyzing raw ultrasound data through a technique called Ultrasound Multiple Scattering (USMS), the researchers aim to create biomarkers that can indicate the aggressiveness of cancers and other conditions like atherosclerosis. This approach seeks to improve the specificity of ultrasound imaging, making it a more effective tool for diagnosing various diseases, particularly in populations where traditional imaging methods may fall short.

Why it matters

Potential benefit: If successful, this research could lead to more accurate cancer diagnoses and better treatment decisions for patients.

How similar studies have gone: Previous studies have shown promising results in using ultrasound imaging for assessing angiogenesis, indicating that this approach has potential for success.

Where this research is happening

  • North Carolina State University Raleigh
    Raleigh, United States
    Active

Researchers

  • Principal investigator: Muller, Marie — North Carolina State University Raleigh
  • Study coordinator: Muller, Marie

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.