Materials and macromolecules tailored for micro and nanoscale chemistry
Official title: Materials and Macromolecules Tailored for Micro and Nanoscale Organic Synthesis
Funded at Wayne State University · NIH-11528798 · Data updated 2026-11-12
A NIH grant proposes making more chemical reactions work better with tiny, automated machines to speed up making complex molecules and drugs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $209,972 |
| NIH project number | 3R35GM157057-02S1 |
| Project ID | NIH-11528798 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients; this is a chemistry/technology development grant.
✕Less likely to help
Patients seeking direct treatments are not the immediate focus of this project.
What this research studies
This project aims to adapt stubborn reagents and big molecules so they can be used with high‑throughput automated systems. Researchers will create stable colloidal forms of insoluble reagents, enabling them to act like liquids in automated workflows. They will benchmark these new methods in important cross-coupling reactions and tackle engineering challenges to integrate them into fast, scalable synthesis. The work focuses on enabling faster discovery and optimization of compounds by leveraging automated experimentation while addressing chemical compatibility limits.
Why it matters
Potential benefit: If successful, this work could speed up the discovery of new drugs and materials by allowing a broader set of chemical tools to be tested quickly and reliably.
How similar studies have gone: Previous high-throughput approaches have accelerated chemical synthesis, but this project targets extending those gains to new reagents and macromolecules.
Where this research is happening
-
Wayne State University
Detroit, United States Active
Researchers
- Principal investigator: Bour, James — Wayne State University
- Study coordinator: Bour, James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.