Mapping treatment for brain cancer using advanced imaging techniques
Whole-brain Spectroscopy Guided Personalized Mapping of Transducer Arrays for Glioblastoma Patients Receiving Tumor Treating Fields
This study is looking to make glioblastoma treatment better by using special imaging to help place devices that deliver electric fields directly to the tumor, which could improve how well the treatment works for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11086607 on NIH RePORTER |
What this research studies
This research focuses on improving treatment for glioblastoma, a highly aggressive brain cancer, by using whole-brain spectroscopy to personalize the placement of transducer arrays for tumor treating fields (TTFields). TTFields are a non-invasive therapy that delivers electric fields to the tumor site, and this study aims to enhance their effectiveness by accurately targeting tumor regions that are often missed in standard imaging. By utilizing advanced computational modeling, the research seeks to increase the dose of TTFields delivered to the tumor, potentially improving patient outcomes. Patients will be monitored closely to assess the impact of this personalized approach on their treatment response.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing treatment with tumor treating fields.
Not a fit: Patients with non-glioblastoma brain tumors or those who are not candidates for tumor treating fields may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and quality of life for glioblastoma patients by optimizing their treatment.
How similar studies have performed: Previous research has shown promising results with similar approaches in optimizing cancer treatments, indicating potential for success in this novel application.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Mohan, Suyash — University of Pennsylvania
- Study coordinator: Mohan, Suyash
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.