Mapping the molecular networks of cancer cells
The Cancer Cell Map Initiative v2.0
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10911935
This study is working to create detailed maps of the genes involved in different types of cancer by looking at data from over 20,000 tumor samples, so that doctors can better understand how these genes affect cancer growth and treatment, ultimately helping to tailor therapies to individual patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10911935 on ClinicalTrials.gov |
What this research studies
This research focuses on creating detailed maps of the molecular networks involved in various cancers, utilizing data from over 20,000 tumor genomes. By analyzing gene mutations and their interactions, the project aims to identify key driver mutations that influence cancer progression and treatment responses. Patients may benefit from personalized therapy approaches based on these insights, as the research integrates advanced bioinformatics and network mapping techniques. The initiative collaborates with leading academic laboratories to enhance understanding of cancer biology.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with advanced cancers, particularly those with unique genetic mutations.
Not a fit: Patients with early-stage cancers or those whose tumors do not exhibit significant genetic mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized cancer treatments tailored to the specific genetic makeup of individual tumors.
How similar studies have performed: Previous initiatives like The Cancer Genome Atlas have shown success in cataloging tumor genomes and identifying genetic alterations, indicating a promising foundation for this research.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KROGAN, NEVAN J — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: KROGAN, NEVAN J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Advanced Cancer, Atlas of Cancer Mortality in the United States