Mapping the brain's structure using advanced data integration techniques
Official title: Functional regionalization of the brain revealed by multi-modal neural and genomics dataintegration
Funded at University of California, San Francisco · NIH-11140227 · Data updated 2026-11-12
This study is exploring how to create a detailed map of the brain by looking at different types of information, like genes and how brain cells connect, which could help us understand brain function better and find new treatments for neurological conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | June 10, 2025 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $338,538 |
| NIH project number | 1R01LM014619-01A1 |
| Project ID | NIH-11140227 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are adults aged 21 and older who may have neurological conditions or are interested in brain health.
✕Less likely to help
Patients with acute neurological emergencies or those under 21 years old may not receive direct benefits from this research.
What this research studies
This research investigates how to accurately map the brain's structure by integrating various types of data, including gene expression and neural connectivity patterns. By analyzing large-scale spatial transcriptomics, the project aims to create a detailed atlas of the brain that reflects the arrangement of different cell types. Patients can benefit from this research as it may lead to new insights into brain function and potential treatments for neurological conditions. The approach involves developing new computational algorithms to handle complex datasets, which will enhance our understanding of brain anatomy.
Why it matters
Potential benefit: If successful, this research could provide critical insights into brain function and lead to improved treatments for neurological disorders.
How similar studies have gone: Previous research from institutions like the Allen Institute and the Broad Institute has shown success in using similar integrative approaches to brain mapping.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Abbasi Asl, Reza — University of California, San Francisco
- Study coordinator: Abbasi Asl, Reza
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.