Mapping lymphatic channels in the arms using advanced MRI techniques
Official title: High-Resolution Lymphatic Mapping of the Upper Extremities with MRI
Funded at Massachusetts General Hospital · NIH-10832087 · Data updated 2026-11-12
This study is exploring a new way to take detailed pictures of the lymphatic system in your arms using advanced MRI technology and deep learning, which could help identify people at risk for lymphedema after cancer surgery, so doctors can take steps to prevent it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $201,000 |
| NIH project number | 5R21EB032932-03 |
| Project ID | NIH-10832087 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have undergone cancer-related surgeries and are at risk for developing lymphedema.
✕Less likely to help
Patients who have not had cancer-related surgeries or do not have a risk of lymphedema may not benefit from this research.
What this research studies
This research investigates a new method for high-resolution imaging of lymphatic channels in the upper extremities using magnetic resonance lymphography (hrMRL). The approach combines advanced MRI techniques with deep learning to create detailed anatomical maps of lymphatic structures in living patients. By understanding the variations in lymphatic anatomy, the research aims to identify individuals at risk for developing lymphedema, a condition often resulting from cancer-related surgeries. This could lead to preventive measures during surgical procedures to reduce the incidence of lymphedema.
Why it matters
Potential benefit: If successful, this research could help prevent the development of lymphedema in patients undergoing cancer surgery, significantly improving their quality of life.
How similar studies have gone: While the approach of high-resolution lymphatic mapping is innovative, similar imaging techniques have shown promise in other areas of medical imaging, suggesting potential for success.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Tsai, Leo Lee — Massachusetts General Hospital
- Study coordinator: Tsai, Leo Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.