Mapping cellular aging in human tissues
Core A: Administrative Core
This study is looking at how aging cells in important parts of the immune system, like the bone marrow and thymus, behave and interact, with the hope that what we learn can help improve the way we manage chronic diseases that come with getting older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10904913 on NIH RePORTER |
What this research studies
This research focuses on understanding cellular senescence, particularly in lymphoid organs such as bone marrow and thymus. A multidisciplinary team will work together to characterize how aging cells behave and interact within human tissues. The project aims to improve our understanding of chronic diseases related to aging by mapping these cellular changes. Patients may benefit from insights gained through this research, which could lead to better management of age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit are individuals experiencing age-related chronic conditions or those interested in the biological processes of aging.
Not a fit: Patients who are not experiencing age-related conditions or who are not interested in cellular aging may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing chronic diseases associated with aging.
How similar studies have performed: Other research has shown success in understanding cellular senescence and its implications for aging and chronic diseases, indicating that this approach is grounded in established scientific inquiry.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Fan, Rong — Yale University
- Study coordinator: Fan, Rong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.