Mapping brain connectivity in marmosets
Official title: BRAIN CONNECTS: Comprehensive regional projection map of marmoset with single axon and cell type resolution
Funded at Massachusetts Institute of Technology · NIH-10922845 · Data updated 2026-11-12
This study is all about understanding how different parts of the marmoset brain connect with each other, which can help us learn more about how brains work in general, including in humans, and it’s designed for anyone interested in brain health and function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 7, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $2,673,932 |
| NIH project number | 5UM1NS132173-02 |
| Project ID | NIH-10922845 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with neurological conditions that affect brain connectivity.
✕Less likely to help
Patients with conditions unrelated to brain connectivity or those who do not have access to the research findings may not benefit from this research.
What this research studies
This research aims to create a detailed connectivity map of the marmoset brain by tracing the pathways of specific neurons using advanced imaging techniques. By employing RNA barcoding and transcriptomic cell typing, the study will identify how different brain regions are interconnected at a cellular level. This comprehensive mapping will help compare brain connectivity between primates and rodents, providing insights into human brain function and disorders. The project will also involve collaboration among leading experts and utilize web-based tools for data sharing and community engagement.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain connectivity, potentially leading to improved treatments for brain disorders in humans.
How similar studies have gone: Other research has successfully mapped brain connectivity in rodents, but this approach in non-human primates is relatively novel.
Where this research is happening
-
Massachusetts Institute of Technology
Cambridge, United States Active
Researchers
- Principal investigator: Feng, Guoping — Massachusetts Institute of Technology
- Study coordinator: Feng, Guoping
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.