Mapping brain connectivity in marmosets
BRAIN CONNECTS: Comprehensive regional projection map of marmoset with single axon and cell type resolution
['FUNDING_OTHER'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-10922845
This study is all about understanding how different parts of the marmoset brain connect with each other, which can help us learn more about how brains work in general, including in humans, and it’s designed for anyone interested in brain health and function.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-10922845 on ClinicalTrials.gov |
What this research studies
This research aims to create a detailed connectivity map of the marmoset brain by tracing the pathways of specific neurons using advanced imaging techniques. By employing RNA barcoding and transcriptomic cell typing, the study will identify how different brain regions are interconnected at a cellular level. This comprehensive mapping will help compare brain connectivity between primates and rodents, providing insights into human brain function and disorders. The project will also involve collaboration among leading experts and utilize web-based tools for data sharing and community engagement.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with neurological conditions that affect brain connectivity.
Not a fit: Patients with conditions unrelated to brain connectivity or those who do not have access to the research findings may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain connectivity, potentially leading to improved treatments for brain disorders in humans.
How similar studies have performed: Other research has successfully mapped brain connectivity in rodents, but this approach in non-human primates is relatively novel.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FENG, GUOPING — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: FENG, GUOPING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders