Making new compounds for treating infections and cancer
Accessing Carbon-based S(VI) compounds via Sulfur-Fluorine (SuFEx) Exchange Reactions
This project aims to create new chemical compounds that could one day help develop medicines for conditions like bacterial infections, cancer, and heart disease.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pomona College NIH-funded |
| Lab location | 1 site (Claremont, United States) |
| Project ID | NIH-11012145 on NIH RePORTER |
What this research studies
Researchers are working on new ways to build important organic molecules called S(VI)-based compounds, which are useful in medicine. Current methods for making these compounds are difficult and limit how they can be modified for specific uses. This project explores a new chemical process called Sulfur-Fluorine Exchange (SuFEx) to more easily create these compounds. By using simple catalysts, the team hopes to develop a more efficient way to produce a wide variety of these molecules, which could then be used in drug discovery efforts.
Who could benefit from this research
Good fit: Patients with inflammatory disorders, cancer, or bacterial infections may eventually benefit from the new drug discoveries enabled by this foundational chemistry.
Not a fit: Patients seeking immediate treatment options will not directly benefit from this basic chemistry research, as it focuses on drug discovery methods rather than clinical application.
Why it matters
Potential benefit: If successful, this work could lead to the development of new and more effective drugs for inflammatory disorders, cancer, and bacterial infections.
How similar studies have performed: Sulfur-fluorine exchange (SuFEx) chemistry is a relatively new and promising pathway, and this project aims to overcome current challenges in its synthetic applications.
Where this research is happening
Claremont, United States
- Pomona College — Claremont, United States (Active)
Researchers
- Principal investigator: Ball, Nicholas D — Pomona College
- Study coordinator: Ball, Nicholas D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.