Making MRI scans of the brain more consistent and reliable across different machines
Harmonizing data acquisition, reconstruction, and analysis for reproducible, cross-vendor, open source MRI
This project aims to create a shared, open-source system for MRI scans to help doctors and researchers better understand brain diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11145819 on NIH RePORTER |
What this research studies
When patients get MRI scans at different hospitals or on different machines, the results can vary, making it harder to spot subtle changes related to brain conditions. This project plans to develop a new, open-source system that works with all MRI machines, from how the scan is taken to how the images are processed. This will help ensure that MRI results are consistent and accurate, no matter where the scan is performed. By making this technology widely available, it will be easier for new MRI methods to be used in research and patient care.
Who could benefit from this research
Good fit: Patients who undergo MRI scans for brain diseases or neuropsychiatric disorders could indirectly benefit from more reliable imaging results.
Not a fit: Patients who do not require MRI scans for brain-related conditions would not directly benefit from this specific technological advancement.
Why it matters
Potential benefit: If successful, this work could lead to more accurate and consistent MRI diagnoses for brain diseases, improving patient care and accelerating research into new treatments.
How similar studies have performed: While the specific "end-to-end" open-source harmonization framework is novel, efforts to standardize MRI data acquisition and analysis have been ongoing, showing the importance of this area.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Rathi, Yogesh — Brigham and Women's Hospital
- Study coordinator: Rathi, Yogesh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.