Maintaining a Special Pathogen Free Primate Colony for AIDS/HIV research
Official title: MAINTENANCE OF THE CLOSED CPRC SPF COLONY
Funded at University of Puerto Rico Med Sciences · NIH-11381106 · Data updated 2026-11-12
A program to keep a colony of carefully screened monkeys ready for AIDS/HIV research, with ongoing health checks and genetic management.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Puerto Rico Med Sciences NIH-funded |
| Lab location | 1 site (San Juan, United States) |
| Project start | July 1, 2016 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $3,820,148 |
| NIH project number | 5U42OD021458-25 |
| Project ID | NIH-11381106 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to patients directly; this is about maintaining a primate research resource used to study AIDS/HIV.
✕Less likely to help
Individual patients will not be directly enrolled or benefited by this grant.
What this research studies
This grant funds the Caribbean Primate Research Center to maintain the SPF colony, including animal care, veterinary services, and careful testing to keep the animals free from specific pathogens. It also supports virology screening and MHC typing to understand the animals’ immune profiles, which helps researchers use the right animals for studies related to AIDS and HIV. The plan emphasizes preserving genetic diversity while enriching for beneficial MHC traits, in line with NIH genetics efforts. The work is about sustaining a resource that enables safer, more reliable biomedical research involving non-human primates. Researchers and staff will follow rigorous protocols to ensure animal welfare and scientific quality.
Why it matters
Potential benefit: This could enable more accurate and safer AIDS/HIV research using well-characterized primate models.
How similar studies have gone: Other SPF primate colonies have successfully supported long-term AIDS-related research with strong genetic and virological controls.
Where this research is happening
-
University of Puerto Rico Med Sciences
San Juan, United States Active
Researchers
- Principal investigator: Ruiz-Lambides, Angelina — University of Puerto Rico Med Sciences
- Study coordinator: Ruiz-Lambides, Angelina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.