NIH-funded research R01 grant

Long-term psychosocial journeys of transgender youth and their parents

Official title: Long-term trajectories of psychosocial functioning among transgender youth and their parents.

Funded at Ut Southwestern Medical Center · NIH-11398030 · Data updated 2026-11-12

This grant follows transgender and gender diverse youth and their parents over time to understand how psychosocial well-being and family dynamics change as GAHT is used.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center
NIH-funded
Lab location1 site (Dallas, United States)
Project startSeptember 25, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$611,467
NIH project number5R01HD112418-04
Project IDNIH-11398030 on NIH RePORTER

Who could benefit from this research

Could help

Transgender and gender diverse youth receiving GAHT and their parents, across diverse backgrounds, with ongoing access to care.

Less likely to help

Youth not receiving GAHT or families not engaged in long-term follow-up may see limited direct benefit.

What this research studies

The project tracks transgender and gender diverse youths who are receiving gender-affirming hormone therapy and follows them and their parents over several years. Researchers will collect information on mental health, quality of life, gender dysphoria, and family stress to see how trajectories unfold in real-world care. The study emphasizes inclusive measurement and considers minority stress and resilience factors in a sociopolitical context. It centers on improving individualized care by understanding within-group differences in long-term outcomes. The work involves regular follow-up visits and surveys to capture changes over time.

Why it matters

Potential benefit: If successful, findings could guide clinicians and families in tailoring long-term care to support mental health and well-being.

How similar studies have gone: Previous short-term data show improvements in mental health, but long-term trajectories remain less understood; this study aims to fill that gap.

Where this research is happening

  • Ut Southwestern Medical Center
    Dallas, United States
    Active

Researchers

  • Principal investigator: Kuper, Laura Elizabeth — Ut Southwestern Medical Center
  • Study coordinator: Kuper, Laura Elizabeth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.