Kidney problems in children after heart surgery
Official title: Kidney-Associated Diseases after Congenital Heart disease surgery In Children
Funded at Johns Hopkins University · NIH-11056732 · Data updated 2026-11-12
This study is looking at the long-term health of kids aged 4-8 who have had surgery for congenital heart disease, especially focusing on their kidney health, to find out how these kids can stay healthier as they grow up.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | March 15, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $631,641 |
| NIH project number | 5R01DK135518-02 |
| Project ID | NIH-11056732 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 4-8 years who have undergone cardiac surgery for congenital heart disease.
✕Less likely to help
Patients who have not had heart surgery or are outside the age range of 4-8 years may not benefit from this research.
What this research studies
This research investigates the long-term health risks, particularly kidney-related issues, in children who have undergone surgery for congenital heart disease (CHD). It aims to recruit 350 children aged 4-8 years post-surgery from four U.S. children's hospitals to form a cohort called CHICKADEE. The study will focus on understanding the relationship between CHD, hypertension, and chronic kidney disease (CKD) to identify risk factors and improve long-term health outcomes. By closely monitoring these children, the research seeks to uncover early signs of kidney disease that may develop as they grow.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management strategies for kidney health in children with congenital heart disease.
How similar studies have gone: Previous research has indicated that children with congenital heart disease are at increased risk for kidney issues, suggesting that this approach to understanding their health outcomes is both relevant and necessary.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Parikh, Chirag R — Johns Hopkins University
- Study coordinator: Parikh, Chirag R
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.