Kidney problems in children after heart surgery

Kidney-Associated Diseases after Congenital Heart disease surgery In Children

NIH-funded research Johns Hopkins University · NIH-11056732

This study is looking at the long-term health of kids aged 4-8 who have had surgery for congenital heart disease, especially focusing on their kidney health, to find out how these kids can stay healthier as they grow up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11056732 on NIH RePORTER

What this research studies

This research investigates the long-term health risks, particularly kidney-related issues, in children who have undergone surgery for congenital heart disease (CHD). It aims to recruit 350 children aged 4-8 years post-surgery from four U.S. children's hospitals to form a cohort called CHICKADEE. The study will focus on understanding the relationship between CHD, hypertension, and chronic kidney disease (CKD) to identify risk factors and improve long-term health outcomes. By closely monitoring these children, the research seeks to uncover early signs of kidney disease that may develop as they grow.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 4-8 years who have undergone cardiac surgery for congenital heart disease.

Not a fit: Patients who have not had heart surgery or are outside the age range of 4-8 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better monitoring and management strategies for kidney health in children with congenital heart disease.

How similar studies have performed: Previous research has indicated that children with congenital heart disease are at increased risk for kidney issues, suggesting that this approach to understanding their health outcomes is both relevant and necessary.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions acute kidney injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.